What is GLP-1?
GLP-1 (glucagon-like peptide-1) has become one of the most talked-about hormones in nutrition and health, largely due to the popularity of GLP-1 medications. However, GLP-1 isn’t something that only comes from a prescription, it is a hormone your body naturally produces every time you eat.
Released by specialised cells in the small intestine, GLP-1 plays an important role in appetite regulation, blood sugar control and communication between your gut and brain. It helps to:
- Promote feelings of fullness
- Slow stomach emptying
- Support healthy insulin release when blood glucose rises
- Reduce glucagon release
- Help regulate appetite and energy balance
Although no food or supplement can replicate the effects of prescription GLP-1 medicines, research shows that your daily habits can help support your body’s own natural GLP-1 response.
1. Start your meals with protein
Protein is one of the strongest natural stimulators of GLP-1.
As protein enters the small intestine it stimulates the release of GLP-1 alongside other satiety hormones including peptide YY (PYY) and cholecystokinin (CCK). These hormones communicate with your brain that you’ve eaten, helping you feel fuller for longer.
Clinical studies reveal that eating protein before carbohydrates also slows stomach emptying, meaning glucose enters the bloodstream more gradually and helping to support steadier energy levels.
Good sources include fish, eggs, poultry, Greek yoghurt, tofu, beans and lentils.
Rejuvenated Tip
Our Protein Smoothie has been developed to make increasing your daily protein intake simple. Each serving provides 23g of plant-based protein, together with glucomannan fibre, prebiotic fibre, green tea and medium-chain fatty acids (MCFAs).
Together these ingredients support satiety, digestive health and healthy metabolism, making it an ideal breakfast, post-workout drink or nutritious snack and an excellent support for GLP-1.
2. Feed your gut microbiome
One of the most exciting discoveries in nutrition science is the role of the gut microbiome in regulating metabolism.
Many fibres, particularly prebiotic fibres, aren’t digested in the stomach or small intestine. Instead, they reach the colon where they become food for beneficial bacteria. As these bacteria ferment fibre, they produce short-chain fatty acids (SCFAs) including acetate, propionate and butyrate.
These compounds act as signalling molecules throughout the body and one role that they perform is stimulating the body’s natural release of GLP-1.
This is one of the ways your gut microbiome communicates with your metabolism.
Rejuvenated Tip
H3O Hydration contains inulin, a well-researched prebiotic fibre that selectively nourishes beneficial bacteria within the gut. Supporting a healthy microbiome helps create an environment where beneficial metabolites, including SCFAs, can be produced naturally.
H3O Hydration → Cellular hydration and gut health (hypotonic electrolytes, inulin, resveratrol, hyaluronic acid and vitamin C).
3. Eat more colour: the power of polyphenols
Polyphenols are naturally occurring plant compounds found in berries, grapes, cocoa, olive oil, herbs, spices and green tea.
Although traditionally recognised as antioxidants, scientists now understand that many of their greatest benefits come from their interaction with the gut microbiome.
Many polyphenols reach the colon where they are metabolised by beneficial bacteria. This relationship supports microbial diversity and encourages the production of compounds that help maintain the gut barrier and influence communication between the gut and the rest of the body.
Emerging research suggests these interactions may influence pathways involved in appetite regulation, glucose metabolism and healthy ageing.
Aim to eat as many different coloured fruits and vegetables as possible each week.
Rejuvenated Tip
H3O Hydration provides resveratrol, a naturally occurring polyphenol found in grapes, while Protein Smoothie contains green tea, another rich source of polyphenols. Together they complement a colourful, plant-rich diet that supports healthy ageing and gut health.
4. Stay hydrated
Hydration affects every cell in the body.
Although water itself doesn’t directly stimulate GLP-1, maintaining hydration supports digestion, nutrient transport, circulation and metabolic function.
Electrolytes help regulate fluid balance, ensuring water is absorbed and distributed efficiently throughout the body.
Rejuvenated Tip
Unlike many electrolyte drinks, H3O Hydration is a hypotonic electrolyte formulation, designed to support rapid cellular hydration. Combined with vitamin C, hyaluronic acid, resveratrol and prebiotic inulin, it supports hydration alongside gut and cellular wellbeing.
5. Support healthy metabolism
Healthy metabolism isn’t determined by one hormone. It depends upon a complex interaction between nutrition, muscle, the gut microbiome, movement, sleep and blood sugar regulation.
Eating balanced meals, exercising regularly and maintaining a healthy weight all contribute to healthy metabolic function.
Looking for targeted supplement support? Read about the specific ingredients in Re-Set that support natural GLP-1 activity.
Rejuvenated Tip
Re-Set has been formulated with carefully selected botanicals and nutrients that support healthy glucose metabolism and metabolic wellbeing as part of a balanced diet and healthy lifestyle. It complements the daily habits that naturally support appetite regulation rather than replacing them.
Re-Set → Healthy glucose metabolism and metabolic wellbeing (botanicals and nutrients that complement a healthy lifestyle).
6. Prioritise sleep and manage stress
Your gut and brain are constantly communicating through what scientists call the gut-brain axis.
Chronic stress increases cortisol, which can influence appetite, blood sugar regulation and the diversity of your gut microbiome. Poor sleep can also alter appetite hormones including ghrelin and leptin, while emerging evidence suggests it may influence GLP-1 signalling.
Supporting restorative sleep, regular movement and stress management helps maintain healthy metabolic function over the long term.
Rejuvenated Tip
Looking after your sleep is an investment in your metabolism. Cellular Calm Complex has been formulated with magnesium, L-theanine and adaptogenic botanicals to support relaxation, restorative sleep and a healthy response to everyday stress—helping you build the foundations for long-term wellbeing.
Cellular Calm Complex → Restorative sleep and healthy stress response (magnesium, adaptogens and calming nutrients that complement long-term metabolic wellbeing).
A whole-body approach to metabolic health
There is no single food, supplement or habit that dramatically increases GLP-1 naturally.
Instead, your body’s natural appetite-regulating pathways are supported by the combined effect of:
- Eating sufficient protein.
- Nourishing your gut microbiome with prebiotic fibre.
- Enjoying a colourful, polyphenol-rich diet.
- Staying well hydrated.
- Exercising regularly.
- Sleeping well.
- Managing stress.
At Rejuvenated, we believe wellbeing is built through small daily habits.
Our products are designed to complement these foundations:
- Protein Smoothie Protein, satiety and metabolic support (protein, glucomannan, prebiotic fibre, green tea polyphenols and MCTs).
- H3O Hydration combines hypotonic electrolytes with inulin, resveratrol, vitamin C and hyaluronic acid to support cellular hydration and gut health.
- Re-Set complements a healthy lifestyle with ingredients selected to support healthy glucose metabolism and metabolic wellbeing.
Together they support a holistic approach to long-term health rather than focusing on one single pathway.
Frequently asked questions
What is GLP-1?
GLP-1 is a hormone naturally released by the small intestine after eating. It helps regulate appetite, supports healthy blood sugar control and promotes feelings of fullness.
Can you increase GLP-1 naturally?
Healthy lifestyle habits, including eating more protein, consuming prebiotic fibre, supporting your gut microbiome, exercising regularly and getting enough sleep—may help support your body’s natural GLP-1 response. These effects are not the same as prescription GLP-1 medications.
Why should I eat protein before carbohydrates?
Protein stimulates GLP-1 and other satiety hormones while slowing stomach emptying, helping support steadier blood sugar levels and prolonged fullness.
How does fibre influence GLP-1?
Beneficial gut bacteria ferment prebiotic fibre into short-chain fatty acids. These metabolites stimulate specialised cells within the intestine that naturally release GLP-1.
What are polyphenols?
Polyphenols are naturally occurring plant compounds found in colourful fruits, vegetables, herbs, spices, tea and cocoa. They support the gut microbiome, healthy ageing and metabolic wellbeing.
Does hydration affect metabolism?
Hydration supports digestion, circulation, nutrient transport and cellular function. Electrolytes help the body absorb and distribute water efficiently, making them an important part of healthy metabolism.
Does stress affect GLP-1?
Chronic stress may influence appetite regulation by affecting cortisol levels, the gut microbiome and communication between the gut and brain. Supporting stress resilience helps maintain overall metabolic health.
Can supplements replace healthy habits?
No. Supplements are designed to complement, not replace, a balanced diet, regular exercise, quality sleep and good nutrition.
